GiveBetter x Denver

Immunize Colorado

Vaccination access partnerships, education and policy

Research time: ~7 min on GPT-6.1 Sol
  • Research — reviewed programs, finances and impact evidence.
  • Modeling — estimated costs, QALYs and uncertainty.
  • Source audit — checked claims, assumptions and calculations.

Updated: 2026-10-07

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Summary

What do they do? Immunize Colorado supports county partners delivering free and low-cost vaccinations, alongside education and policy work. Its 2025 Shots for Tots and Teens partnership delivered 1,355 doses to 440 patients, mostly school-age children. The coalition also supports other access programs, but their patients and policy effects are not automatically added to this clinic cohort.

Why we’re interested in this organization:

  • Original 2025 patient and IRS reports give matched annual outputs and recipient cost.

  • Original efficacy and economic research distinguish actual disease prevention from clinic attendance and retail vaccine value.

  • Patient health and household resource units remain distinct, with shared illness-risk/efficacy gates and full participation losses.

Our main reservations:

  • Mixed vaccine types, completed protection, incremental uptake and patient residence are not observed.

  • The seasonal infant efficacy trial and lifetime birth-cohort model cannot calibrate this mostly school-age catch-up clinic directly.

  • Whole coalition cost against one supported clinic channel omits unknown portfolio benefits and potentially important partner delivery costs.

What do you get for your dollar? $3.2M per DALY in Denver. DALY is our one-year comparison unit. QALY-based health gains and income-welfare equivalents retain their original assumptions; they are not measured clinical DALYs. Matched FY2025 full coalition annual cost against a conditional supported Shots for Tots and Teens channel; not whole portfolio or next-gift effectiveness..

Original 2025 patient report: 440 patients, including 388 children, 49 adults and three age-missing. Clinic county totals are location, not resident geography; doses and other partner channels not added.

1. What do they do?

Immunize Colorado, EIN 84-1479975, supports county health partners offering vaccination access, education and policy. Shots for Tots and Teens works with Jefferson, Adams, Arapahoe and Boulder county health departments. Receiving a supported vaccination is not automatically coalition-caused additional protection. Public VFC, Medicaid, insurance and other clinics are substantive alternatives.

2. Monitoring and information sharing

The original 2025 report gives 440 patients and 1,355 doses across 25 clinics, not 1,355 independent people. Age counts are 388 children (348 aged 4–18), 49 adults and three missing. Reported county patient totals sum to 438, and comparative clinic-count text is inconsistent; these do not justify precision about residence or annual performance. The 272 un/underinsured, 118 Medicaid, 25 privately insured and 18 CHP+ patients are not all otherwise paying retail prices. Request vaccine mix, full protective series, resident county, household deduplication, additional uptake, illness outcomes, partner costs and donor expansion capacity.

3. Qualitative assessment

The original Pepin trial randomized children aged 6–35 months to two doses 28 days apart. Any-strain influenza efficacy was 50.98% among 4,980 per-protocol participants; it does not establish mixed-vaccine efficacy for the predominantly 4–18-year-old clinic cohort. The original CDC 2024 economic model uses nine routine vaccines over lifetime birth cohorts, historical prevaccine disease risks and costs including premature-death productivity. Its 10.9 societal benefit-cost ratio and survival earnings are not imported. These sources support vaccination and caregiver illness-cost mechanisms, not local QALY calibration. The retained clinical reference explicitly decomposes the earlier .003 untreated expected morbidity-year into judged .2 annual illness risk and .015 healthy-year loss per illness. Mixed efficacy .8 remains a judgment, not a transfer of the infant trial. The original seasonal flu-risk sensitivity instead uses .05 risk, seven days at .5 utility and trial .5098 efficacy; it yields no positive finite price under the retained participation costs. Other partnership, policy and education effects remain unknown, not zero.

4. What do you get for your dollar?

FY2025 full recipient expense remains $571,433 ($569,413 functional plus $2,020 netted event costs). The 2024 and 2023 full expenses are $895,442 and $746,555, mean $737,810. The conditional reference changes from $3.1M to $3.2M per DALY: health remains .2066283 equivalents while signed household resources change from approximately −.0240868 to −.0258509 because illness savings now require vaccine efficacy as well as illness risk. This is dependency correction, not evidence the coalition performed worse. Whole coalition cost includes unquantified other services. The $222,806 recognized mixed outreach/program sensitivity is not allocated clinic full cost or a marginal gift price. Partner clinical/public vaccine resources can be material and are separately tested, not presumed covered by this nonprofit expense.

Model, assumptions and sensitivity

Full calendar FY2025 coalition IRS expense including netted direct event costs, against partial supported patient benefit. Partner delivery costs and other channels unmeasured; not full social portfolio EV.

Judged .75 share in pinned ten-county Denver CBSA19740, based on metro clinic anchors but without recipient residence data; statewide activities not fully assigned to Denver. New detailed county counts describe clinic locations (including Boulder), not residence; .75 remains judged.

Health = (patient N × b × eligible × completion × efficacy × illnessRisk × episodeQ × finite discounted health duration − full delivered patient harm) × local share. Resource illness cases = household N × unique × age share × b × eligible × completion × illnessRisk × efficacy. Same household-year signed gains/costs jointly logged, full access burden for all households; per delivered patient partner resources and distinct payer loss localized once.

C
571433 USD annual (observed). Original FY2025 full recipient functional cost plus netted events, not partner delivery budget. [finance]
N
440 annual supported vaccination patients (observed). Original supported 440 annual patients, not doses or all coalition channels. [patient-mix]
unique
0.8 households per supported patient (judgment). Judged income-household grouping only; clinical patients and partner per-patient costs are not reduced. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
eligible
1 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
completion
0.9 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
b
0.3 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
response
0.8 model parameter (judgment). Judged .8 mixed efficacy, applied once to untreated morbidity and illness cash cases; original infant influenza trial informs separate .5098 sensitivity only. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
T
1 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
g
0.75 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
delay
0.1 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
r
0.03 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
harm
0.00002 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
illnessRisk
0.2 model parameter (judgment). Judged .2 annual untreated illness risk, not observed local vaccine-specific incidence; shares efficacy gate with income. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
episodeQ
0.015 model parameter (judgment). Judged .015 healthy-year loss per illness; product with .2 risk retains prior .003 expected morbidity hypothesis, not empirical local QALYs. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
workGain
40 model parameter (judgment). Judged $40 net sick-work resources conditional on avoided illness for caregivers/adults, no child wages. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
medicalGain
10 model parameter (judgment). Judged $10 otherwise-paid illness cash avoidance conditional on disease prevention, not retail vaccine value. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
overlap
0.5 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
cost
5 model parameter (judgment). Judged $5 net additional participation cost relative to alternative clinics, full regardless of benefit. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
baseline
20000 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
payerLoss
0 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
externalCost
0 model parameter (judgment). Additional unrecognized partner resource per delivered patient, independent of household conversion or series completion; zero central not proof no cost. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
payerPeople
10000 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
payerBaseline
50000 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
childShare
0.8818181818181818 model parameter (observed). Observed patient age composition; conversion to separate post-dedup caregiver/adult household groups remains judged. [patient-mix]
adultShare
0.11136363636363636 model parameter (observed). Observed patient age composition; conversion to separate post-dedup caregiver/adult household groups remains judged. [patient-mix]
caregiverWorkMultiplier
1 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]
adultWorkMultiplier
1 model parameter (judgment). Explicit conditional judgment with null/adverse/scope sensitivities, not a measured recipient causal coefficient. [services] [patient-mix] [vaccine-trial] [vaccine-economics] [cg-cost]

central: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no illness risk: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

illness risk high: Cost: $571K; Denver health QALYs: 0.42; all-population health QALYs: 0.56. Income-equivalent healthy years: -0.02. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

short illness loss: Cost: $571K; Denver health QALYs: 0.07; all-population health QALYs: 0.10. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

longer illness loss: Cost: $571K; Denver health QALYs: 0.38; all-population health QALYs: 0.51. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

payer on failed completion: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.36. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

payer on zero efficacy: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.36. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

clinical patient no household dedup: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.02. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no caregiver work resource: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no adult work resource: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no age known resources: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

flu season risk example: Cost: $571K; Denver health QALYs: 0.02; all-population health QALYs: 0.02. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

lower morbidity risk: Cost: $571K; Denver health QALYs: 0.00; all-population health QALYs: 0.00. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

clinical null: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

financial only: Cost: $571K; Denver health QALYs: 0.00; all-population health QALYs: 0.00. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

zero benefit full burdens: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no exposure: Cost: $571K; Denver health QALYs: 0.00; all-population health QALYs: 0.00. Income-equivalent healthy years: 0.00. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no gift no exposure: Cost: $0; Denver health QALYs: 0.00; all-population health QALYs: 0.00. Income-equivalent healthy years: 0.00. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

adverse: Cost: $571K; Denver health QALYs: -3.07; all-population health QALYs: -4.09. Income-equivalent healthy years: -0.17. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

unknown: Cost: unknown; Denver health QALYs: unknown; all-population health QALYs: unknown. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no recipient resources: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

clinical response null: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

short health: Cost: $571K; Denver health QALYs: 0.05; all-population health QALYs: 0.06. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

longer protection: Cost: $571K; Denver health QALYs: 0.61; all-population health QALYs: 0.82. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

low additionality: Cost: $571K; Denver health QALYs: 0.06; all-population health QALYs: 0.09. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

all additionality: Cost: $571K; Denver health QALYs: 0.70; all-population health QALYs: 0.94. Income-equivalent healthy years: -0.01. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

half geography: Cost: $571K; Denver health QALYs: 0.07; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.01. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no local share: Cost: $571K; Denver health QALYs: 0.00; all-population health QALYs: 0.00. Income-equivalent healthy years: 0.00. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no positive overlap: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

full positive overlap: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.02. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

negative overlap zero: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.07. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

negative overlap one: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.07. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

mixed resources: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.06. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no access cost: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: 0.01. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

high access cost: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.32. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

higher payer incidence: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.04. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

higher volunteer opportunity: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.35. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

double cost: Cost: $1.1M; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

recognized mixed community program cost: Cost: $223K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

half connections: Cost: $571K; Denver health QALYs: 0.10; all-population health QALYs: 0.14. Income-equivalent healthy years: -0.01. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

higher connections: Cost: $571K; Denver health QALYs: 0.31; all-population health QALYs: 0.41. Income-equivalent healthy years: -0.04. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

household deduplication: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.02. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no net work gain: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

higher after cost work: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: 0.04. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no eligible subgroup: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no completed dose: Cost: $571K; Denver health QALYs: -0.01; all-population health QALYs: -0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

low clinical response: Cost: $571K; Denver health QALYs: 0.01; all-population health QALYs: 0.01. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no copay otherwise paid: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

three full year mean cost: Cost: $738K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

low completed dose: Cost: $571K; Denver health QALYs: 0.02; all-population health QALYs: 0.02. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

no volunteer opportunity: Cost: $571K; Denver health QALYs: 0.21; all-population health QALYs: 0.28. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

full completed dose: Cost: $571K; Denver health QALYs: 0.23; all-population health QALYs: 0.31. Income-equivalent healthy years: -0.03. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

Counterfactual: VFC, Medicaid/private insurance, local public health and other clinical providers without coalition support; access and trust barriers may leave additional patients.

Attribution: Coalition b .3 and series completion .9 are judged; delivered doses are observed but completed protective series and additional uptake are not. Risk .2 and mixed efficacy .8 jointly govern both avoided disease and illness resources, with .015 illness utility loss. Efficacy is applied once, not twice.

The .003 expected untreated morbidity reference is retained for continuity, not resolved by generic evidence. Clinic vaccine mix, incremental access, baseline illness risk, duration, adult/caregiver household resources, residence and partner costs remain decision-changing unknowns.

Sensitivity

  • no illness risk: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • illness risk high: $1.4M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • short illness loss: $12.6M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • longer illness loss: $1.6M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • payer on failed completion: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • payer on zero efficacy: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • clinical patient no household dedup: $3.0M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no caregiver work resource: $3.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no adult work resource: $3.2M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no age known resources: $3.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • flu season risk example: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • lower morbidity risk: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • clinical null: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • financial only: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • zero benefit full burdens: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no exposure: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no gift no exposure: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • adverse: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • unknown: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no recipient resources: $3.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • clinical response null: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • short health: $27.4M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • longer protection: $971K per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • low additionality: $16.8M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • all additionality: $823K per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • half geography: $9.5M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no local share: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no positive overlap: $3.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • full positive overlap: $3.0M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • negative overlap zero: $4.2M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • negative overlap one: $4.2M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • mixed resources: $3.8M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no access cost: $2.7M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • high access cost: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • higher payer incidence: $3.4M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • higher volunteer opportunity: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • double cost: $6.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • recognized mixed community program cost: $1.2M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • half connections: $6.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • higher connections: $2.1M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • household deduplication: $3.1M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no net work gain: $3.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • higher after cost work: $2.3M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no eligible subgroup: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no completed dose: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • low clinical response: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no copay otherwise paid: $3.2M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • three full year mean cost: $4.1M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • low completed dose: no finite positive estimate. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • no volunteer opportunity: $3.2M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.
  • full completed dose: $2.8M per DALY. Conditional FY2025 Shots for Tots and Teens supported patient envelope. Vaccine mix, unique household conversion, series protection, illness risk, coalition contribution, net resources and residence share are judgments. Other policy and education channels unknown.

Unresolved inputs

  • Vaccine/age mix and unique completed protection
  • Causal coalition additional uptake
  • Actual household resources and partner/public incidence
  • Measured CBSA recipient residence
  • Allocated support cost and marginal funding capacity

Health and income breakdown

For the modeled $571K: 0.21 health QALYs + -0.03 income-equivalent healthy years in Denver: $3.2M per DALY. Income equivalents are welfare comparisons, not observed QALYs or DALYs.

Method and caveats.

5. Funding and previous grants

The current own donor page links https://childrensimmunization.app.neoncrm.com/forms/default-donation-form-individual; its exact endpoint returned HTTP 200, without a donation transaction. Reduced public-health capacity and clinic outreach funding are reported constraints, not proof any gift produces a specified patient cohort. Clinical benefit uses all patient units; resources alone use .8 judged household grouping and pediatric-caregiver/adult shares. The $40 net sick-work resource gain refers to caregiver work for pediatric cases or adult patients, after taxes, benefits and work costs—not child wages or survival earnings. The $10 illness-medical saving means otherwise-paid cash, not vaccine retail value. Both illness savings require incremental eligible completed protection, .2 illness risk and .8 efficacy. All exposed households retain $5 judged net additional access/time cost relative to other vaccination routes, and all delivered patients retain process harm even when protection fails. Same household-year work/medical savings less access costs are jointly logged; only positive gains receive .5 overlap adjustment. Signed resources remain negative centrally. Clinical utility-null and biological efficacy-null are distinct: the former can retain avoided illness cash while the latter removes illness savings. Income covers one illness season; longer health protection is a health-only duration sensitivity, not repeated future wages. Extra partner cost is per delivered patient and survives failed completion, efficacy or household deduplication. Global payer/provider loss associated with local recipients is included once; no duplicate recognized recipient costs or full retail vaccine transfer is assumed.

Annual expenses

Organization-level spending, including programs, administration and fundraising. The research list averages three comparable, consecutive full fiscal years when available.

  • FY 2025: $571K; org:immunize-colorado, 12-month period, IRS full functional expenses plus netted direct event expenses. Source
  • FY 2024: $895K; org:immunize-colorado, 12-month period, IRS full functional expenses plus netted direct event expenses. Source
  • FY 2023: $747K; org:immunize-colorado, 12-month period, IRS full functional expenses plus netted direct event expenses. Source

6. Sources

  1. Current supported clinic locations and VFC/public alternatives. Immunize Colorado. Published: not stated; retrieved: 2026-10-06.
  2. 2025 annual supported vaccination patient envelope. Immunize Colorado. Published: not stated; retrieved: 2026-10-06.
  3. FY2025 original full annual IRS cost. IRS original filing. Published: not stated; retrieved: 2026-10-07.
  4. FY2024 original full annual IRS cost. IRS original filing. Published: not stated; retrieved: 2026-10-06.
  5. FY2023 original full annual IRS cost. IRS original filing. Published: not stated; retrieved: 2026-10-06.
  6. Current legal EIN and donation intake link. Immunize Colorado. Published: not stated; retrieved: 2026-10-07.
  7. Health and signed net income comparison framework. Coefficient Giving. Published: not stated; retrieved: 2026-10-06.
  8. 2025 original patient age and clinic-county report. Immunize Colorado. Published: not stated; retrieved: 2026-10-07.
  9. Original placebo-controlled seasonal influenza efficacy trial. Pepin et al., Vaccine / Elsevier; original trial abstract in PubMed. Published: 2019-03-22; retrieved: 2026-10-07.
  10. Original modeled health and economic benefits of routine childhood immunizations. Zhou et al., CDC MMWR. Published: 2024-08-08; retrieved: 2026-10-07.